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Craniofacial Sutures: Development, Diseases and Treatment

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Craniofacial Sutures: Development, Diseases and Treatment

D. Rice(EDT) | Karger

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Sutures are more than just fibrous joints between the bones in our skull. They are active growth sites that influence the development, growth and shaping of our face and cranium. When suture development is disrupted, craniosynostosis can result, a condition which is characterized by the premature closure of one or more cranial sutures before brain growth is complete and leads to an abnormally shaped skull. In this publication, leading experts in the field, both researchers and clinicians, discuss suture morphogenesis from developmental, evolutionary and genetic perspectives. In addition, an appraisal of the molecular etiology, clinical presentation and treatment of craniosynostosis is presented, as well as an outlook to future areas of study and to innovative therapeutic philosophies.

In this volume craniofacial developmental and evolutionary biologists, oral and maxillofacial surgeons, orthodontists as well as pediatric and plastic surgeons will find a wealth of recent information on the field of craniofacial development, deformity and its treatment.


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Foreword by M. M. Cohen, Jr.
Preface by D. P. Rice
Developmental Anatomy of Craniofacial Sutures by D. P. Rice
Locate, Condense, Differentiate, Grow and Confront: Developmental Mechanisms Controlling Intramembranous Bone and Suture Formation and Function by D. P. Rice and R. Rice
Mechanical Influences on Suture Development and Patency by S. W. Herring
Suture Neontology and Paleontology: The Bases for Where, When and How Boundaries between Bones Have Been Established and Have Evolved by M. J. Depew and C. Compagnucci and J. Griffin
Single Suture Craniosynostosis: Diagnosis and Imaging by J. Hukki and P. Saarinen and M. Kangasniemi
Clinical Features of Syndromic Craniosynostosis by D. P. Rice
Genetics of Craniosynostosis: Genes, Syndromes, Mutations and Genotype-Phenotype Correlations by M. R. Passes-Bueno and A. L. Sertie and E. S. Jehee and R. Fanganiello and E. Yeh
Roles of FGFR2 and Twist in Human Craniosynostosis: Insights from Genetic Mutations in Cranial Osteoblasts by P...

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